Children born to mothers older than 35 are more likely to have heart problems - even if they were conceived from eggs frozen years earlier

• Children born of mothers over 35 are more likely to have weaker cardiovascular systems, University of Alberta researchers found
• Both the age of eggs and of the placenta contribute to these changes 
• This means that even women who conceive through IVF are at risk 
• A woman's age raises her risks of preeclampsia 
• Babies born to older women may be less resilient to 'second hits' of environmental factors that that alter the way their genes are expressed
•  
•  
  People whose mothers had them after age 35 may be more likely to have heart problems, new research suggests.
  University of Alberta researchers studied female rats that give birth to offspring with impaired blood vessels and greater risk of heart problems as adults, the University of Alberta study found.
  As more women focus on their careers earlier in life and reproductive medicine advances, the number of babies born to women over 35 is surging. 
  The children of women who undergo IVF or use frozen or donor eggs are still at risk of cardiovascular problems, as both the age of the egg and the placenta play a role in the development of the fetus's system of blood vessels. 
  'This research is important because it improves our understanding of the impact of giving birth at an older age on the health of offspring in later life,' said lead study author and executive director of the Women and Children's Health Research Institute, Dr Sandra Davidge. 
  
  
  Children whose mothers gave birth to them after the age of 35 are at higher risks of cardiovascular issues later in life, a new study of
  But, she says, these greater risks should not scare older women away from having children, just be used to help them better prepare for pregnancy.  
  Having a baby at an older age has long been known to come with unique risks., Women who become pregnant over 35 are more likely to have children with growth difficulties and chromosomal abnormalities, such as Down's syndrome.